KNOXVILLE, Tenn. (AP) — Republican Congresswoman Marsha Blackburn and Democratic ex-Gov. Phil Bredesen are set to clash in their second — and likely last — U.S. Senate race debate this year in Tennessee.

The debate Wednesday will take place at the University of Tennessee's Howard H. Baker Jr. Center for Public Policy.

Nexstar Media Group TV stations will broadcast the event live.

Bredesen and Blackburn previously faced off in a Sept. 25 debate at Cumberland University in Lebanon.

The two are competing in a race to replace retiring Republican Sen. Bob Corker. The contest could be pivotal in deciding whether Republicans hold a 51-49 Senate majority.